Repetitions performed in a resistance training (RT) set lie on a continuum whereby the maximum termination point is ‘momentary muscular failure’. Set termination can also occur a specified number of repetitions from momentary muscular failure, known as ‘repetitions-in-reserve’ (RIR).

 

RIR is an important variable that not only influences physiological adaptations to RT, such as skeletal muscle hypertrophy, but also short-term responses (e.g., neuromuscular fatigue and perceived discomfort) that may negatively influence performance and adherence.

 

The aim of this thesis was to address research limitations surrounding the application of proximity-to-failure during RT and further explore its influence on muscle hypertrophy, neuromuscular fatigue, and perceptual responses, allowing for improved practical guidelines.